Hello to you all, my name is Jordan. I have created this account on behalf of my father, Paul. He is 57 years old. 2 years ago he was diagnosed with Stage 4 Colo-rectal cancer and given 3 months to live. We live in Cardiff, Wales along with his loving wife Tamara and 9 year old son (my brother) Kristian. My dad is the backbone of our family and we could not bear the thought of losing him. So, we are all fighting day and night for his survival, researching whatever treatments and therapies we can find across the world.

He has been battling the disease for the past 2 years and it has truly been a heartbreaking roller-coaster of a journey throughout. We have given almost all of our money into trying to cure him but there are still more treatments out of our reach financially. We need all the support we can get from anyone out there. It’s inconceivable to imagine life without him, especially for my little brother, Kristian.

Our aim with this fund is to help him access life-saving treatments not available on the NHS and to provide support for him throughout his battle. Every penny goes towards medical plans, therapies and everyday maintained of his condition and health. AS A FAMILY WE HAVE ALREADY SPENT CLOSE TO £30,000 THE PAST 18 MONTHS ON VARIOUS HOME THERAPIES,RIFE MACHINES,INFRA RED SAUNA INSTALLED,OZONE MACHINES and numerous other treatments. These may have helped halt the progression. The doctors are still amazed my father is alive and healthy, but if the disease continues to progress we have been told he has less than 6 months. Time is of the essence.

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To give you a backstory and timeline of events, my dad was diagnosed in June 23rd 2017 by an oncologist in Cardiff after years of misdiagnosed IBS. He was told he had Stage 4 KRAS-Wild type cancer starting with a large 10cm tumor in his lower intestine which had metastasized to his liver, forming several smaller tumors all over the organ. As it would be for anyone, this was devastating news for him and all of us, especially facing a prognosis of only a few months left to live.

Struggling to cope with this reality, we all agreed that we would drastically change my father’s diet and lifestyle to attempt to combat his ill health. Going down a natural/alternative route, we incorporated vegetable/fruit based juices and foods, regular exercise and complete removal of alcohol/toxic substances. This change led him to become a lot healthier, less fatigued and focused on overcoming this disease. But as should be expected with cancer, it turned a blind eye to these efforts and still continued to grow. By September 2017, despite our reluctance, he was placed on heavy-duty chemotherapy in an attempt to shrink the tumors. This strategy would hopefully put him in line for liver resection, which was the gold-standard in curative treatment as suggested by the doctors.

The chemo had thankfully shown us signs of shrinkage and a drop in CEA levels (protein released by cancer cells; indicative of growth/activity) in the blood stream. We were getting ideal results and were elated over the prospect. But just when we could seen glimpse of the finish line, a serious complication struck in the form of a perforated bowel, leading my father to be rushed into hospital by myself on November 13th. He was experiencing excruciating pain in the abdomen, making him barely able to walk, move or talk. The hospital doctors had discovered the lining of his intestine had burst open just above his colon tumor, causing a release of intestinal toxins and waste into his blood stream. He was at a high risk chance of it developing into peritonitis, then sepsis and lastly death.

He was scheduled to be rushed into an operation that would only sever the bowel just before the hole in his intestine, leaving him with colostomy bad but a high chance of spreading cancer all across his body. Fortunately, due to miraculous circumstances, he was recommended into a different advanced surgery by the top colorectal surgeons in the hospital the day after. This opportunity was a blessing in hindsight. The brilliant surgeons were able to completely remove his large colon tumor (which we had been working towards to shrink so that surgery was possible), several infected lymph nodes and successfully disconnect the intestines. The panic was over. Despite the harrowing ordeal, he survived the operation and was set on the long road to recovery for the next month or so. His souvenir for all this, if you will, was a huge, stitched up incision in the center of his abdomen and a colostomy hole which he still has to this day. A small price to pay in some respects. He spent the Christmas period of December 2017 recovering at home.

As you can guess, however, we were not out of the woods yet. Scans on January 18th 2018 had shown an increase in his liver tumors and burden, going from 7 lumps to 11. We put this down to his complete inactivity and relatively poor but crucial diet in the month of recovery prior. So, more harsh chemotherapy ensued and we focused on a lot of alternative methods that would aid in killing the cancer. We spent thousands of pounds in the hope that a lot of these natural/alternative products would work against his cancer. Despite seeing some stability, the cancer was not responding as we’d hoped.

March 2018 led to a change in his chemo regime, swapping it to a different combination. By this point he was really feeling the negative side effects of the drugs, i.e nerve damage to hands and mouth, chronic fatigue, brain fog, destroyed immune system, etc. Fortunately, this cycle of chemo had shown favorable results, shrinking the tumors to the lowest sizes to date and his CEA count to it’s lowest number of 14. The finish line was in sight again, we were gaining considerable ground.

In April 2018, after a meeting with his oncologist, it was suggested he could take a break from his treatment for a couple of weeks. The response was ideal and was in line for the resection operation, which was the end goal. However, one liver tumor straddling the portal vein in the liver was the only complication, putting a hold on the operation.

His body had been battered by the drugs, despite how he’d handled it a lot better than most. There are even side effects he’ll have for the rest of his life, but it’s the price you pay for a chance of cure. We used this time to help him repair his body and spirit, taking more time away from work, eating/living healthy and using natural treatments on the side. The break amounted to a total of 5 weeks until his next scan on May 10th. We had anticipated a stable disease, with no progression under the advice of the doctors. We were wrong. Everything had grown and there were signs of new smaller tumors forming around the liver. CEA count had also risen but fortunately there was no further metastasis outside of the liver.

It was a shock result and was hard for my father to deal with. He made the decision to taken a further cycle of chemotherapy, this time a different regimen to counter the resistance the cancer has shown to the previous. After a few cycles of this cycles of this, his CEA markers continued to rise, indicating progressive disease (further growth) and the therapy was not having any effect. The scan on July 10th confirmed our fears as terrifyingly, the tumors had increased again, even the smaller ones. Following this, he was taken off chemotherapy.

It was a dark and upsetting period in our lives, not knowing which way to turn or what to do. There was no clear pathway to follow or any signs of hope. We continued diligently with alternatives treatments, throwing ever ‘cancer cure’ we could get at it. Amongst the confusion, we stumbled upon treatments that were taking place across Europe. More specifically treatment centers and the one that we put our faith in was in Wrocław, Poland. The center is a state-of-the-art alternative medicine clinic that provides non-conventional therapies to patients of many different diseases. Therapies such as curcumin injections, local or full-body hyperthermia treatment, IV vitamin C and many others. We had researched this clinic and treatments and were incredibly optimistic at the results they have had. So, after much debate, my father used all of his remaining savings, even had to sell personal belongings and booked a flight straight to Poland on October 12th 2018.

(Link to example of Clinic)

He stayed for 2 weeks of treatment out there which cost him around £8000, a lot of money! They gave him many infusions and heat treated his liver several times. He had high hopes after his arrival back home and was eager to receive favorable results from his next scan on November 2nd. We maintained a strong belief that God was on our side and showing us the right path. But as you can guess by now, we were in line for another crushing defeat. The devastating results had shown, to our amazement, substantial growth of all tumors, along with a CEA count rise. This was one of the biggest blows to our family of all. So much time, money and faith had been placed into this treatment plan but we were met with worse results than expected. Furthermore, if matters couldn’t seem any worse, he was taken to hospital with extreme liver inflammation which we presume came from the hyperthermia. A traumatic lesson to learn.

The situation was overwhelming . The oncologist had suggested he would have only months left before his liver would start shutting down. But, through all the sorrow and anguish he meets, my father remained a true fighter and did not greet his disease sitting down, waiting for it to kill him. The battle has been ongoing for just over a year at this point. Statistically he should be dead. Unlike most people, however, he kept pushing and fighting for a cure.

During this period, there was even talk about having liver transplant surgery in India. Being in touch with lots of doctors, saying how good the outcomes were for patients and that it almost guarantees a cure. We were contemplating raising £30,000 to afford it, but we were unsurprisingly struck back down again after being told that transplantation cannot take place with liver metastases, only primary liver cancer. Another waiver of hope burnt in front of us.

The weeks that followed, we further concentrated on more alternative methods and products. We still used a lot of natural compounds and other therapies we had bought equipment for such as Ozone, RIFE and Infrared Saunas. With a lot of anecdotal evidence for these treatments, we had just hoped for the best yet again. As usual, however, the scan on November 23rd gave us evidence of more progression, matched with a drastic rise in CEA levels, 914 (the highest yet). You can imagine that in our eyes, there is literally nowhere to turn at this point. We had practically zero options available to us, with palliative/hospice care being organised for my father. How do you really accept the end? Where is the point of no return? These were questions circulating through both of our minds. But the refusal to accept death from the start is the reason he is still here today. I strongly believe that.

The overwhelming feeling that something out there, amongst the thousands of compounds, chemicals and treatments surely has the ability to cure his cancer. We all shared it and it drove us back into the battle, spending countless hours researching into a plethora of scientific trials, journals and discoveries. Within the haystack, we discovered a needle in the form of a specialised, targeted test for individual cancer cells, known as the Greek test (RGCC test). This one of a kind test offers a person the chance to discover exactly what is going on with their tumors/cancer, the activity of different genes/expressions and more importantly, testing which chemotherapy and natural drugs show the highest effectiveness against their particular cancer.

The test was known to my father briefly before, but was ignored and pushed aside after mentioning it to his oncologist earlier in the year. We discovered that this technology (the measuring of Circulating Tumor Cells) was a hallmark invention in predicting patient outcomes and creating personalised treatment plans that are more effective that standard, conventional ones.

Link: https://www.rgcc-group.com/

The test is used worldwide by different oncologists and takes place within labs in Switzerland and Greece. Of course it is met with a price, which was £1900 in total for the full testing of hundreds of drugs and gene expressions. So, after days of debating and researching into this test, we came to the conclusion that this could be our last hope of finding a cure. It was a very stressful period on the run up to Christmas, so this would have been a huge thing to undertake and fund. But we put our heads together and decided to go for it as time was running out.

So, on December 17th, we just about managed to pay the fee and his blood samples were sent through the RGCC Bristol office over to Switzerland then Greece. We all managed to enjoy a lovely Christmas over this period. Grateful for the joy and presents for what could be his last.

The results, after what felt like forever, finally came to us at the start of the New Year on Jan 5th. We were very excited to view the reports (which will be attached for all to see). To our amazement, there were several big-hitting chemo drugs that worked very well against his cancer. As well as this, the natural compounds they tested (e.g Ascorbic Acid, Curcumin, Lycopene, etc) also displayed a degree of different reactions with his tumor cells. The genes and expressions report did, however, show a lot of resistances to drugs and a high cell growth and spreading rate. But we were elated by these findings. It gave us a clearer understanding of how his cancer works and exactly what works against it. For example, the drug Cetuximab, given to generally all colorectal cancer patients as a standard treatment, including my father throughout the year, showed no apoptopic (killing) response at all. It was eye opening at how everyone’s cancer can be different and have more resistance to some drugs than others.

This test, for us, creates a beacon of light in an otherwise dark crossroads. It shines the way and opens us up to new possibilities and understandings. They say knowledge is power, and in terms of cancer, it means survival. So with this knowledge, we hope to accurately and scientifically treat my father in hope that he survives this terrible disease. The war is not over for us and the dream of him being cancer free is what keeps us going every day. However, as strong as our will is, financially we have been very much weakened this past year. We don’t currently have the income or means necessary to help fund any further treatments that could save Paul. This is why we are asking for anyone out there who can understand our situation to hopefully help our cause. My father is too proud to do this himself, so I’ve made the decision myself to create this fund.

*UPDATE JAN 2019* - Latest scan results have shown progression of disease which was upsetting but generally expected as he has not been on a proper treatment schedule. However, his CEA count had dropped from 914 to 578 following one round of chemotherapy on December 17th, which is a good sign. After speaking with his oncologist and discussing his RGCC results, he is now scheduled to start a more targeted regime of chemo on the 28th Jan. This regimen consists of an old but effective drug called Mitomycin C (injected ever 3 weeks) and daily oral intake of a strong anti-metabolite known as Capecitabine. We have our fingers crossed that he can tolerate this next round and we can achieve considerable shrinkage.

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Our list of foreseeable financial costs are as follows:

1.Home care/supplements

-Natural Compounds and Supplements suggested by RGCC , these include - Vascustatin (Bindweed extract), Artemesinin/Artesunate (Malaria Drug), Paw-Paw (Potent Exotic Fruit), Certain Mushroom Species and many other types of natural compounds. Along with potential IV injections and other compounds, the cost of all this totals at around £1500-2500 a month.

-Costs of travelling and consultations with important doctors and integrative oncologists who can maintain his protocol and monitor his health.

-Maintenance costs in the form of helping to purchase organic vegetables, juices, liver friendly products and exercise equipment.

Example: https://www.abelandcole.co.uk/fridge/ready-meals

2. Chemotherapy/Private Drugs

-Avastin (Bevacizumab) - This is a recent Monoclonal Antibody (MOAB) and is a targeted therapy. VEGF inhibiting drug not available to my father on the NHS due to cost. Shown by the RGCC test and many scientific studies, it has a great effectiveness against his cancer cell line. For us to purchase privately, it roughly works at £2000 a month which is unfortunately beyond our means.

-Stivarga (Regorafenib) - Another targeted drug, classed as a Small Molecular Weight (SMW) molecule, it works by blocking proteins on tumor cells that encourage growth. It’s an oral PKI inhibiting and anti-angiogenesis drug on the NHS that is not currently available to my father. So the private costings total to around £5000 for 1 month of treatment. Too expensive for the NHS funding, but they are cooperating with monitoring if it was bought privately.

3. Possible Advanced Alternatives Treatments

-Trans-Arterial ChemoEmbolization (TACE) therapy - a relatively new form of administering chemotherapy drugs into the body. Instead of systemic chemo, it is directly injected into the main vein that supplies the liver tumors their blood supply. This has been shown to be incredibly effective in many trials and studies, some with even complete remissions after 3 cycles. The current private cost for this in Germany in around £5000 per cycle.

-Local Thermal Ablation Techniques - Brand new technology that uses frequencies to induce heat related necrosis (death) of tumour cells. There are a few different types, such as Microwave (MWA) and Radiofrequency (RFA) ablation, but the most advanced Laser-Induced Interstitial Thermotherapy (LITT). This patented technique comes with a relative price tag, dependent on treatments and cycles, of around £6000 - £12,000 and would take place at hospitals in Germany, etc.

-Irreversible Electroporation (IRE) (NanoKnife) - A very recent form of cancer treatment, available only to patients with relatively small tumours and a low burden. It also uses thermal ablation techniques, but it’s main technique is to destroy cancer cell membranes with the use of electromagnetic pulses, causing apoptosis (cell suicide). There are machines available on the NHS, but criteria is difficult to meet in the UK to be eligible. The private cost would work out at around £13,500 for a few tumors.

-CyberKnife - similar to NanoKnife, it uses an advanced robotic machine that targets individual tumors, but instead destroys them with radiation therapy. This form of radiosurgery is very effective at dissolving tumors without damaging surrounding tissue. Currently only available to a select criteria of people on the NHS, of which my father apparently does not qualify. So to afford this treatment privately in world class hospitals across Europe, you’d be looking at £10,000-15,000 in countries like Latvia or Germany.

So, with all this information, we hope you can see that we are genuine and seeking true, curative treatments recognised globally by science. All we truly desire is for my dad to be cured of this disease or at least an extension of his time with us. He has a really good chance due to his cancer being only confined to his liver. Time is of the essence, as his liver will rapidly begin failing if nothing can be done. We understand the risks but we also understand the science behind cancer and treatments against it. I believe he can beat this and I hope you can to!

So from the bottom of our hearts, we thank you for taking the time to read this and can only update you on his progress in the coming months.

There is always hope.

Kind Regards,

Jordan and the rest of the Jones family x