About Primary Immunodeficiency Association

Children and adults born with a primary immunodeficiency have little or no natural defence against infections, resulting in chronic, long-term illness. PiA is the only charity in the UK dedicated to helping people living with these rare and debilitating conditions. We represent over 100 primary immunodeficiencies ranging in severity, as recognised by the World Health Organisation. PiA actively campaigns to raise awareness, and to ensure that people have access to the best possible care and treatment. We provide specialist information, guidance and support, including literature, welfare and benefits advice, residential activities and a helpline. We work closely with the leading centres of excellence for the treatment of people with primary immunodeficiencies, including the Institute of Child Health and the Children’s Bone Marrow Transplantation Unit at Newcastle General Hospital. In recent years, children suffering from more serious immune disorders, such as ‘boy in the bubble’ syndrome, have been given new hope for survival through pioneering gene therapy and bone marrow transplants, research for which has been funded by PiA. We are a founder member of the national Jeans for Genes campaign, which helps children with severe, often incurable, genetic disorders.