500 miles aims to provide support and care for amputees and other disabled people in deprived parts of the world through the provision of prosthetic treatment, mobility equipment, community care projects and education. The charity raises money in the UK and provides grants to suitable projects around the world, wherever the need is most great.

Ace is a national disabled children's charity that aims to inform, support and train parents and professionals in the use of technology for young people who have communication difficulties, both in speaking and/or writing.

ASSERT provides support to the individuals and families who are affected by Angelman Syndrome. This is done by sending out information packs, producing a regular newsletter and providing a helpline to support families and professionals.

ARCOS exists to improve life for children and adults who have communication and/or swallowing problems, their families and others involved. Many clients have complex, life-long disabilities. Its goal is to enable them to benefit from the latest advances in knowledge, understanding, skills and technology.

Autism Cymru is a purely Welsh charity. All Trustees live in Wales and it is staffed by Welsh based practitioners. In recognition of its work Autism Cymru was S4C's Charity of the Year during 2006. Its key strategic work includes raising Public awareness of autism throughout Wales; lobbying Welsh and UK governments to introduce specific policies and strategies for autism; providing comprehensive bi-lingual information on autism to families through awares.org, delivering training throughout Wales; setting-up a Welsh centre for autism research; projecting Welsh autism issues in the EC and playing a key role in setting-up the EC's forthcoming European Autism Alliance.

The Bendrigg Trust runs high quality courses and holidays for disabled and disadvantaged people. It aims to promote integration, encourage independence and build self-confidence through the use of residential experience and the safe provision of adventurous activities delivered by dedicated, qualified staff.

BREADLINE facilitates churches in Moldova and Siberia to develop ministries, which bring glory to God and have a lasting impact on their communities; including; evangelical missions, agricultural projects to help poor farmers attain sustainable livelihoods, advocacy for the disabled, and centres which protect young people at risk from trafficking.

CandoCo Dance Company is the world’s leading dance company of disabled and non-disabled dancers. CandoCo reaches over 16,000 people each year, giving opportunities to disabled young people to access the arts. Our participants develop greater self-confidence and have a better quality of life through activity that is not traditionally offered.

Capability Scotland is the country’s leading disability organisation working for a just Scotland. We work with children, adults and families living with disability to support them in their everyday lives. Capability Scotland works with disabled people, their families and carers for a fair and just Scotland by influencing policy legislation, practice and attitudes.

DELTA believes that the vast majority of deaf children can learn to listen and talk and that all parents of deaf children should be given this option. It's aim is to promote the education of hearing imparied children through the use of their residual hearing capacity and through the development of a naturally spoken language.

Two babies are born every day with Down's syndrome. Through information and support for people with Down's syndrome, their families and professionals, the Down's Syndrome Association helps these people live full and rewarding lives.

Dyslexia Action (Formerly the Dyslexia Institute) is a national charity and the UK’s leading provider of services and support for people with dyslexia and literacy difficulties. We specialise in assessment, teaching and training. We also develop and distribute teaching materials and undertake research. We are committed to improving public policy and practice. Our mission is to ensure that individuals with dyslexia are identified and educated to allow them to be successful.

Free children’s clinics for the diagnosis and treatment of reading difficulties. Provides accurate and unbiased information on latest research to educational/health professionals, media and general public in UK and internationally. Supports academic researchers – developing the skills and knowledge needed to continue scientific advance in the study of dyslexia.

Employment Opportunities for People with Disabilities is the charity with the sole aim of helping people with any sort of disability find employment. Its staff are specialists in understanding the issues surrounding disability and employment and during 2004 it helped more than 1,300 disabled people find or experience work, and helped a further 2,000 people with work related queries.

FQMS works to advance medical education throughout Palestine and the medical school at Al Quds University, Jerusalem, supporting visiting lecturers, examiners, teaching materials, student and faculty participation in conferences, clinical supervision, specialist training, the development of e-learning & video conferencing, shelter for students on clinical rotation under curfew.

The Grace Eyre Foundation is a charity local to Brighton and Hove in East Sussex. It provides day opportunities and accomodation services to adults with learning disabilities and has done so for over 100 years. We are constantly striving to provide better services to increase levels of confidence and independence for our service users.

The Harris Bursary Fund, part of the University of Central Lancashire Foundation, supports UCLan students who are in dire need of help to fund their studies. Support is given in various forms including such things as computer equipment, book tokens and luncheon vouchers.

The Hornsey Trust offers Conductive Education to children with Cerebral Palsy. It provides group and one to one parent and child sessions, a nursery and a school for 5-11 year olds. It aims to help each child be as independent as possible by developing their physical, intellectual and social abilities.

Set up in 1978, Impact Initiatives is delighted to be celebrating its 30th anniversary this year. Impact Initiatives aims to improve independence through promoting learning and supporting health.The key areas are advocacy, children and young people’s services, housing and support for young women, older people’s services and specialist vocational support.

John Grooms is a national disability charity, which provides brain injury rehabilitation, nursing and residential care homes and wheelchair accessible housing to over 10,500 disabled people in the UK each year. Training opportunities and accessible holiday properties also enables those affected by disability to have greater independence.

The Kepplewray Project is an education and activity centre for disabled and non-disabled people. Kepplewray challenges exclusion and is founded on a commitment to bring disabled and non-disabled people together as equal partners.

The Resource helps pupils and young people with Autistic Spectrum Disorders (ASDs) to access the curriculum. It also provides young people with ASDs help and support to gain paid employment.

It provides educational services, vocational training opportunities and residential care for children and adults with learning disabilities.

The Laburnum Boat Club is a community-based boating project by the Regents Canal in Hackney. Set up by local parents in the early eighties, the Club runs a programme of water-based activities throughout the year - primarily for children, young people and their families - but also for local community, education and welfare groups.

It provides and installs solar powered lighting into educational establishments in the developing countries. The most recent recipients are a school in Zambia, one in Rwanda and one in Ghana. It has also put lighting into several establishments in Kenya. It's next project, in November, will be in the Phillipines.

The charity operates both a primary school and a secondary school in Beddington, South London, for pupils aged 5 - 19 with speech, language and communication difficulties.

Livability creates choices for disabled people and brings life to local communities. We offer a wide range of services to around 8,000 disabled people and their families, including residential care, supported living, education and accessible holidays. We also provide community organisations with the resources, advice and confidence to transform their neighbourhoods. Livability is a new charity, created by the merger of John Grooms and the Shaftesbury Society, two charities which have been hard at work among the UK’s most marginalised people for over 160 years.

The Lombard Rally, organised in partnership with The Endurance Rally Association, is an unforgettable test of skill, communication and teamwork. This year's Rally is helping to raise vital funds for TreeHouse, the national charity for autism education. By sponsoring a team, you will be helping to fund road safety facilities at our new National Centre for Autism Education.

The Meadow School for Steiner Education strives to nurture the development of the whole child through education in an environmentally, socially and economically sustainable school, working collaboratively out of an anthroposophical impulse.

MS Research Training and Education raises funds to enable research that will address its aims and further progress in the treatment of MS. In addition the charity will promote and support training and education to further knowledge and involvement of those who live with MS and those who treat it.

It provides opportunities to improve and change the lives of Romania's poorest people by providing health education, a family planning clinic and ante and post natal care. It runs a day centre for children with special needs and a young volunteers program including guiding and scouting. A rehousing program for the poorest.

The National Autistic Society exists to champion the rights and interests of over half a million people with autism and to ensure that they and their families receive quality services appropriate to their needs.

The National Star College provides further education and independence training to young people from across the UK aged 16 to 25 with physical disabilities or acquired brain injuries.

The Nystagmus Network is a registered charity run by volunteers and one part-time employee. It relies on donations and members' subscriptions to enable us to provide support to people with the eye condition nystagmus and to promote research. It currently support several projects in the UK, covering ophthalmological research, genetics and possible drug therapies.

We are a service provider offering accommodation, employment, leisure activities and community support for children and adults with disabilities towards independence and lead fulfilled lives within theri communities.

The Orpheus Centre is a residential arts and learning centre for young disabled people. It provides opportunities for personal development through participation in performing arts and life-skills training.

The Oxford Radcliffe Hospitals (ORH) Charitable Funds is the umbrella charity for over 700 funds supporting projects across the ORH NHS Trust that enhance services and facilities for patients and staff. These range from support for particular wards, at the John Radcliffe, Churchill and Horton Hospitals, to larger fundraising campaigns to support major developments such as the new Oxford Cancer Centre, the Oxford Children's Hospital, the Geratology Appeal and the Oxford Heart Centre expansion. As one of the foremost teaching trusts in the UK, the Oxford Radcliffe Hospitals enjoy a national and international reputation in fields such as cancer and cranio-facial surgery. Please give generously - your support enables us to provide the best possible healthcare in the best possible setting, to a standard far higher than the NHS alone would be able to afford.

What’s so special about PACE? Simple, team work! Every child’s achievement, is a direct result of our unique staff team - all working together in one centre with the child at its heart. We believe in each child’s ability to learn despite their disability. PACE is a charity that provides a loving environment and inspirational programmes in order to motivate children with physical disabilities such as cerebral palsy to work hard at achieving their goals. Currently about one in every 400 children in the UK is affected by cerebral palsy and its rising. Please help PACE change lives today.

A national residential specialist college for students with a wide range of physical disabilities and associated learning difficulties. Portlands ethos is extremely positive based on minimizing the effects of the disability and focusing on the potential and aspirations of each individual, rather than the disability.

QAC provides education, training and support towards employment for blind and partially sighted people and those with other disabiltiies. Learners and clients are aged 16+. The charity also develops people's social and independence skills in a day or residential setting.

Rainbow House helps children with physical disabilities between the age of 3 months - 16 years to become more active & independent through Conductive Education and Early Years services, aiming to achieve each childs goal in sitting, standing and walking and improve their social skills in eating, dressing and toileting, making integration into mainstream school and the community easier. Not only do we help children with disabilties such as Cerebral Palsy, Downs Syndrome, Metabolic & other genetic motor disorders, we also provide support for their families & carers.

Penn School is a secondary school for children aged between 11-18 years with communication difficulties associated with hearing impairment and/or speech and language difficulties who may have additional physical or learning problems. For more information please visit the web site (www.pennschool.bucks.sch.uk)

HD is a hereditary disease which slowly destroys the ability to control and co-ordinate movement and thought. About 6,000 people in Scotland are symptomatic or at risk of developing the disease. SHA aims to significantly improve their quality of life through expert Advisory Services, specialist information and Family Support Groups.

Sense is the UK's largest organisation offering support to deafblind people and their families. Established in 1955 as a parent's support group, Sense now offers a range of services - including, advice, housing, education and practical help to children and adults who are both deaf and blind.

Shaw Trust is a national charity providing training and work opportunities for people who are disadvantaged in the workplace due to disability, ill health or other social circumstances. They focus on what people can do not what they cannot and believe that everyone should have an equal opportunity to work.

The Snowdon Award Scheme helps physically and sensory impaired people meet the extra costs of studying in further and higher education. Students with places at UK colleges and universities can apply for help with costs such as sign language interpreters, notetakers, computers and other specialised equipment and service needs.

The Sophie Centre is a charity and inclusive pre-school for children aged 2.5 to 4 with and without disabilities/ special needs. It helps children in wheelchairs and with other physical disabilities, cerebral palsy, autism, visual impairment and developmental delay. It receives up to 50% of its funds from Lambeth Education, Nursery Education Grant and from fees but still needs to find over 50% of our core running costs every year from fundraising to keep the centre running and to continue our valuable work.

SPIRIT is a charity dedicated to promoting best practice in spinal injury medicine and treatment and the rehabilitation of individuals who have suffered spinal injury. We promote teaching and training at specialist spinal injury centres to enhance the quality of treatment of spinal cord injured individuals.

St Elizabeth's specialises in providing lifelong education and care for children, young people and adults with Epilepsy, Autism, neurological disorders and associated disabilities. The centre consists of a School, College and Residential Home. People are accepted according to need regardless of faith, culture or ethnic background.