In June 2008 my cousin Skye Wellesley, was diagnosed with Rett Syndrome. Rett Syndrome is caused by a sporadic genetic mutation on the X chromosome. This microscopic change in the structure of chromosomal proteins has an overwhelming impact on the life of the 1 GIRL in 15,000 statistically around the world. Most obviously, Rett chronically slows these girls neuro-development, very few Rett girls will ever speak and only half of them will walk. Behind the physical incapacity, there are also additional problems as Rett girls are prone to scoliosis, difficulties with digestion, epilepsy and fits of extreme anxiety. My cousin Skye sadly died on 12 Dec 21. She was 15.