Charlie is 27, the same age as my older daughter. He lives near us in Sussex. When he was a toddler he had a brain tumour that nearly killed him. You can read about it on the charity's website.

His family set up Charlie's Challenge to fund research into childhood brain tumours. With no administration costs, all the money raised is spent on vital research projects vetted by a scientific and medical panel comprising experts from around the UK.

Charlie is thriving; I had a pint with him before Christmas.