HELPING TO FIGHT CANCER WITH A 100% NATURE BASED CREATION - BE PART OF SOMETHING GROUNDBREAKING!

Bare Native is passionate about helping increase the speed and success of traditional cancer treatments for cancer patients everywhere. We believe we have the solution by complimenting traditional drugs with our 100% natural mineral composition which we call our Nano Nutrient Matrix (NNM).

We are on an incredibly exciting journey, and we need your help to move it forward.

Bare Native is creating a new kind of business – one which changes our planet positively using nature to help heal us, and the world we live in. Founded in 2018 by Abigail Gibson, Bare Native created and developed a unique natural composition. This composition is derived purely from mineral material. This Nano Nutrient Matrix has already proven to reduce inflammation in human skin models of psoriasis and eczema, as well as to purify the dirtiest of waters through its filtration properties.

More recently, as a biotech science company, Abigail has seen the benefits of the Nano Nutrient Matrix and wanted to take it even further. Partnering with Cancer Research, and working with highly experienced scientists, strategists and creatives, alongside Canterbury Christchurch University, we have the privilege of discovering the anti-inflammatory properties this matrix has when combined with cancer cells.

We can’t let this groundbreaking discovery stay in the laboratories anymore – and through networks and collaborations like crowdfunding, we want to tell the world and take our findings to the wider market.

Cancer is undoubtedly one of the deadliest diseases that has affected mankind. It is yet to be fully understood but in this technological era, where fast-paced innovations constantly open up new avenues for cancer diagnosis, subsequent treatment and also cancer care, there are small businesses like Bare Native who are making a difference.

Our results so far indicate that the matrix, in combination with anti-cancer drugs, has an incredible synergy and promotes cancer cell death. In our experiments to date, we see cancer cell death within 24 hours at 50% acceleration.

We need your help to fund critical further research to develop our innovation practices to help us develop, quantify and verify the impact of our Nano Nutrient Matrix through our educational partners at Canterbury Christ Church University, UK. You could save a life with your donation today.

We are looking to raise £200,000! These funds go towards:

Further Research and Development - Equipment - Laboratory Space - Resources - Legal and Insurance - Just Giving fees

MASTERS RESEARCH AT CANTERBURY CHRIST CHURCH UNIVERSITY

Lung cancer is the leading cause of cancer death worldwide killing over 1.2 million people each year with NSCLC being the most common form (75-85% lung cancer patients)1. Uveal melanoma (UM) is the most common primary adult intraocular cancer2. It is a rare but lethal cancer, with almost 50% of the patients developing metastatic disease3; a quarter of these in the lung. Improvement in the management of these lethal cancers at both the early diagnosis and therapeutic stratification levels requires a better understanding of the biological mechanisms governing the tumours’ metastatic potential. 

The inflammatory pathways play an important role in both the initiation and progression of many human diseases such as cancer at various sites in the body4. The inflammatory response has been classified either as acute or chronic and is described in many human diseases. In the case of acute inflammation, this is initiated within minutes to hours and days proceeding with damage to tissue which may be caused by an immune response or by physical force. While chronic inflammation usually results over a longer period and is a result of pro-inflammatory activators. Hence, chronic inflammation has been associated with diabetes, rheumatoid arthritis, atherosclerosis, and cancer5-7. Therefore, perturbing the production of pro-inflammatory mediators is paramount in the development of treatment of various inflammatory diseases such as cancer.

Our previous studies indicate the NNM can reduce inflammation in a human skin model of psoriasis and eczema. The goal of this study is to investigate the anti-inflammatory potential of NNM.

1. Does NNM have anti-inflammatory effects in lung cancer and uveal melanoma models?

2. Can NNM affect cancer cell growth and cell migration?

3. What are the mechanisms and anti-cancer components of NNM?

References

1. Woodman C, Vundu G, George A, Wilson CM. Applications and strategies in nanodiagnosis and nanotherapy in lung cancer. Semin Cancer Biol. 2021 Feb;69:349-364.

2. Coupland SE, Lake SL, Zeschnigk M, Damato BE. Molecular pathology of uveal melanoma. Eye (Lond). 2013 Feb;27(2):230-42.

3. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249.

4. Schetter AJ, Heegaard NH, Harris CC. 2010. Inflammation and cancer. Carcinogenesis 31: 37-49.

5. Guo LY, Hung TM, Bea KH, Shin EM, Zhou HY, Hong YN, Kang SS, Kim HP, Kim YS. 2008. Anti-inflammatory effects of schisandrin isolated from the fruit of schisandra chinensis baill. J Pharmacology 597: 293-299.

6. Ljung T, Lundberg S, Varsanyi M, Johansson C, Schmidt PT, Herulf M, Lundberg JO, Hellstrom PM. 2006. Rectal nitric oxide as biomarker in the treatment of inflammatory bowel disease. World J Gastroenterol 12: 3386-3392.

7. Watanabe K, Kawamori T, Nakatsugi S, Wakabayashi K. 2002. COX-2 and iNOS, good targets for chemoprevention of colon cancer. Biofactor 12: 129-133.