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Eleftherios Kyriacou raised £11,556 from 45 supporters


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Closed 06/03/2019

raised of £10,000 target by 45 supporters

    Weʼve raised £11,556 to "Genome 21 project"

    Funded on Wednesday, 6th March 2019

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    In 1959 the French doctor Jerome Lejeune identified the cause of DS as the presence of 3 copies of human chromosome 21, instead of the normal 2, in the cells of the affected individuals. This condition has been called trisomy 21. This discovery gave the origin to the field of medical genetics. Studying in detail the mechanism of the syndrome becomes possible, in particular how the presence of an extra chromosome 21 can be associated with the symptoms, in view of a possible pharmacological intervention as a therapy for trisomic subjects. Prof. Lejeune firmly believed in the possibility to find a therapy, currently investigated by a limited number of research groups.

    "We will beat this disease. It's inconceivable that we won't. It will take much less intellectual effort than sending a man to the Moon. If I find out how to cure trisomy 21, than that would clear the way for curing all the other diseases that have a genetic origin." (Jérôme Lejeune, 1926-1994).

    On April 22nd 2016, the team supervised by Dr Pierluigi Strippoli ( published a paper about the “critical region” for Down syndrome in the Human Molecular Genetics. The study suggests that the region responsible for the main symptoms of Down Syndrome corresponds to only one-thousandth of the whole chromosome 21.

    Funding for this research was influenced by limited availability of funds for local experimental research and by the intense efforts toward prenatal diagnosis oriented to selective abortion rather than toward basic and applied research aimed at finding effective therapies. For this reason, every contribution is crucial to support the research activities of the Laboratory.



    Eleftherios Kyriacou

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      5 years ago

      Eleftherios Kyriacou started crowdfunding

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      Page last updated on: 12/15/2018 18.33



      • Stefano Carinelli

        Stefano Carinelli

        Dec 15, 2018

      • leonardo grosso

        leonardo grosso

        Dec 10, 2018

        please accept this little sign of gesture..don't give up ..carry on..relentlessly


      • Anonymous


        Dec 1, 2018



      • RS


        Nov 30, 2018

        Uniti si vince! Thanks for the initiative and keep fighting till you achieve the goal!


      • Marchese


        Nov 30, 2018

        Best of Luck with your research Professore ! hopefully a huge brake through soon !

      • Anonymous


        Nov 28, 2018

        Well done Alberto & Team to organize such event and for promoting such cause. Clearly an eye opener in terms of the amount of work behind and great learn. Thank you and best of luck for the project!


      • Francesco di Giura

        Francesco di Giura

        Nov 27, 2018

        Excellent project for an excellent cause. Thanks Alberto for promoting it!


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      Eleftherios Kyriacou

      Eleftherios Kyriacou

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