In July 2025, our 11-month-old son, Charlie, was diagnosed with PolG mitochondrial disorder — a rare, degenerative disease with no effective treatments and no cure.

This devastating condition affects every part of his life, and as parents, we are determined to fight for hope, research, and a future where no family has to hear the words "there is no cure."

That is why Harrison (Charlie's father) together with family and friends*, will be running the Yorkshire Marathon on 19 October 2025 — to raise vital funds for The PolG Foundation, whose mission is to support and accelerate research to find effective treatments and a cure for PolG mitochondrial disorders.

With your support, we can fund groundbreaking research, raise awareness, and hopefully bring Charlie closer to effective treatments and a cure.

Thank you in advance for your support.

Harrison & Ellie.

* Family and friends also running for Charlie: Max Brook, James Nettleton, James Dodds, Emily King, James Williams, Archie Naylor, Charlie Beachell, Joe Porter, Emily Ward and George Binnington.