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James Nash

James Nash is crowdfunding

raised of £45,000 target by 276 supporters

Weʼre raising £45,000 to Help me to raise funds towards the only medical treatment available for my Primary Progressive Multiple Sclerosis (PPMS)

Oswestry, Shropshire

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Hi, my name is James and I am 47 years old. My wife and I have four wonderful children. In January 2021 I was rushed to hospital after collapsing, unable to use my legs. Four days later I returned home with a diagnosis of Primary Progressive Multiple Sclerosis (PPMS).

I don't qualify for any treatment on the NHS for my type of MS. Whilst we often hear of people suffering with bad days and good days, my MS is progressive so every day my symptoms get worse with no respite. At diagnosis my EDSS was 2.5. - 15 months later it is 6.5.

Whilst most MS causes lesions on the brain, mine is attacking both my brain and spinal cord and has left me virtually confined to a wheelchair. The short term doesn't look good. At the rate that I am progressing it wont be long before I am completely bedbound, unable to feed myself and my mental capacity will diminish.

Hematopoietic stem cell transplantation - HSCT

HSCT treatment has been around for a long time Russia and Mexico currently lead the way having researched and provided treatment for many years. Here in the UK we have only started researching and running trials this year. As it is so limited and my MS is progressive, I don't qualify for the trials. My MRI’s continue to show no active lesions on my brain (common in PPMS and one of the reasons it is so hard to treat). Despite a lack of active lesions, I have extremely aggressive progression of my illness. HSCT treatment is effective in 70% of patients with PPMS. HSCT aims to 'reset' the immune system to stop it attacking the central nervous system. It uses chemotherapy to remove the harmful immune cells and then rebuilds the immune system using a type of stem cell found in your bone marrow. These are the haematopoietic stem cells.

HSCT is not a cure but it does however, have a 70% chance of halting the progression. As every day passes I am losing more and more of my chance to live any kind of meaningful life. I want to continue to work in the job I love, to support my family and to be the best dad I can to my 4 wonderful children. Time is not on my side.

Together with my wife, we have been researching HSCT treatment in Mexico. They will only accept patients with an EDSS of 6.5 so it is now or never. With this in mind, we have provisionally booked a date of 28th August 2022 when I will fly out to Mexico for 28 days to receive treatment. The cost is around £45,000 and in addition I have to fund flights, a full time carer for the duration of my stay in Mexico and provide MRI scans. Provided the treatment goes well and I have no complications, I will be unable to work for at least 5 weeks and after that period I will still have to isolate and work from home which puts an extra financial burden on my family.

Every penny we can raise towards this treatment will help immensely. This is my only chance and I would like to thank anyone who reads my story as awareness for this cruel illness is vital for progression of research and any future treatments that may become available on the NHS. For me, there is no more time to wait. It really is now or never.

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  • James Nash1 month ago
    James Nash

    James Nash

    1 month ago

    I am amazed (and completely shocked) to be able to confirm that the final balance for my trip to Mexico has been covered in full via my employers. An incredible gesture by the insurance industry. Flights booked, treatment covered and only 55 days to go until my journey begins. Never could I have imagined the kindness and generosity of the people that I know and love, and many more people that I have never even met. Humanity in faith - just incredible! Thank you so much to everyone who has donated and supported me in my journey! ☺️

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  • James Nash2 months ago
    James Nash

    James Nash

    2 months ago
    Update from the Page owner

    25% reached. Thank you so much for all of your support. We are overwhelmed ♥️

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  • James Nash2 months ago
    James Nash

    James Nash

    2 months ago
    Update from the Page owner

    Share this update to help us raise more

3 months ago

James Nash started crowdfunding

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Page last updated on: 8/5/2022 20.41



  • Emily


    Aug 5, 2022

    James, I am literally sitting in the chemo room at Clinica Ruiz in Mexico. I hope you can get here too… I’ll miss you by a week! Very best wishes

  • Andrew


    Aug 5, 2022

    Good luck mate, wishing you all the very best


  • Sunny Tang

    Sunny Tang

    Jul 7, 2022

    Hope this little donation will be helpful in a little extent. Get well soon!

  • Penny and Andy Harris

    Penny and Andy Harris

    Jul 4, 2022

    Sending our love and prayers, as well as a donation xx

  • Karen


    Jun 30, 2022

    I wish you all the best with treatment James and hope it stops the MS in its tracks. Thinking of you all xx


  • Anonymous


    Jun 29, 2022

    Wish I could give more. Good luck to you and your family


  • Guinevere and Holbache House

    Guinevere and Holbache House

    Jun 28, 2022

    Wish you all the best :)


James Nash

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About the fundraiser
James Nash

James Nash

Oswestry, Shropshire

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