Thanks for taking the time to visit my JustGiving page.

I'm raising funds to help support the Pancreatic Cancer Research work being carried out at the Freeman Road Hospital Newcastle .

Our family is indebted to the marvellous work that they carry out and their support during last year was fantastic .

I know we can't turn back the clock , but if I can help raise money to go towards helping into the research for pancreatic cancer then it will go some way to helping other families like ours so any support you can give would be greatly appreciated . 

Pancreatic cancer is diagnosed in 6000 people in the UK annually and is the fourth most common cancer.  Acinar cell cancer (ACC) of the pancreas however, is a very rare type of pancreatic cancer representing <1% of all pancreatic cancers. Only about 10-25 cases per year are diagnosed in the UK.

The treatment for these are cancers is surgical resection (where possible) and chemotherapy. In practice the chemotherapy (Gemcitabine and or Capecitabine) that is given to patients with ACC is given to them as it is the chemotherapy that has shown, in trials, to be effective in treating patients with the most common (>95%) type of pancreatic cancer (adenocarcinoma).

The optimal chemotherapy to give to patients with ACC is not known.

A major obstacle in investigating the potential role of different chemotherapy agents in the treatment of ACC are the small number of cases available in each individual specialist centre.

Pete’s Pancreas Project in conjunction with the research team at the specialist HPB surgical centre at the Freeman Hospital Newcastle aim to:

Set up a UK registry of ACC based at the Freeman Hospital.

Collect retrospective and prospective demographic, treatment and outcome data of patients with a diagnosis of ACC

Facilitate the movement of histological tissue samples from other specialist centres to the Freeman Hospital for analysis

This will enable

Examination of detailed data about ACC in the UK to provide the most comprehensive information for clinicians and patients

Results from detailed pathological analysis of specimens will provide information regarding the potential role for chemotherapy agents

Our panel of tests will look at 20-30 chemotherapy agents

We will then be able to construct individual ‘chemotherapy signatures’ i.e know exactly which chemotherapy agents are likely to work for each individual patient

Chemotherapy agents that are frequently detected to have a potential effect will be noted. Such combination therapy could then be used for future patients and results collated

A standard chemotherapy regime may then be constructed to be used nationally and internationally

This analysis has never been done before.

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