Mast cell activation syndrome (MCAS) is a condition which can develop in children or adults. In people with MCAS, mast cell chemicals called mediators are released too frequently or abundantly, and/or in response to triggers that are not typically considered to be harmful such as foods or chemicals in the environment. This leads to a wide range of symptoms that affect multiple systems in the body.

Specific triggers and symptoms of MCAS vary greatly between individuals, and additional triggers can include fragrances, exercise, stress, and changes in temperature. MCAS symptoms can come and go and may often change over time within the same person. This can make it difficult for people with MCAS to identify their specific triggers, and the number of triggers and severity of symptoms may continue to increase as the condition progresses. At present, there is no cure for MCAS.

Mast Cell Action is the only UK charity providing support, information and guidance specifically and exclusively to the MCAS community and health professionals.

Charity founder, Gawain Paling says: People with mast cell activation syndrome are caught in a diagnostic Odyssey for years. They bounce around the system seeing one specialist after another - often for decades - until they find one doctor that is prepared to join the dots and take them seriously. It's just not good enough.

If it involves moving, then do it while Moving 4 Mast Cell! Have fun, collect some sponsor money and don't forget to take lots of photos so we can see what you've been up to. Sign up today to run a marathon, do a skydive, take a coastal walk - or choose your own movement to help us fight MCAS. Get in touch to receive your free charity t-shirt plus any other support you need to run your event!

MCAS can limit many things in life, but your love gives us all vital hope for a brighter tomorrow. Thank you for being there for our community.