Will Luker, David Lytton, Julia Payne, Karishma Patel, Sarah Brown, Simon Hood, Stephen Brennan, Sarah Alderson, Rob Rees, Ben Adamson, Aden Doran, Katie Willis, Stephanie Bird, Rachel Severn and Michael Stewart are taking part in a Tough Mudder this October to raise funds for Jake. Please give generously if you are in a position to do so.

About Solving Kids' Cancer

At Solving Kids Cancer, we fight for a future where no child dies of neuroblastoma or suffers due to its treatment. Neuroblastoma is a rare but and aggressive paediatric cancer that affects around 100 children each year in the UK. Approximately 50% of those children will have the high-risk form of neuroblastoma, which has a very high relapse rate and a survival rate which has remained at or below 40%.

We are there for families of children affected by neuroblastoma, providing support throughout their cancer journey and helping them with the widespread challenges they face. We provide specialist information to help families choose the best treatment options for their child and to access treatment if its not available on the NHS.

We also enable innovative clinical research to give children fighting the disease access to the best treatment options closer to home. We do all of this so that children have a better chance of beating this aggressive disease once and for all, and we are determined to find a cure for future generations.

About Jake

Your fundraising will support in particular 5-year-old Jake Cohen, who was diagnosed with neuroblastoma in July 2017. Initially, brave little Jake had eight rounds of chemotherapy. But his parents were told that he had not responded sufficiently to move on to the next stage of the treatment plan. So he had another two rounds of a different chemotherapy. But it was the same story still making progress, but not to the level needed.

Jake is now classed as having refractive neuroblastoma, which means he has not responded sufficiently to standard frontline treatment. So he's had lots of additional chemo and three cycles of MIBG therapy, which involved spending three weeks in a lead-lined room in radioactive isolation at UCLH.

"Watching your child going through intensive cancer treatment is horrific. Every drug Jake has received has potential long or short-term side effects and he has spent more time in hospital than most people do in their lifetime. However, he deals remarkably well with everything that is thrown at him and he has a happy positive outlook on life. We are lucky that he is no different to any other 5-year-old boy in that respect", say Hannah and Adam, Jake's parents.

Fundraising Campaign

As Jake's family know, high-risk neuroblastoma is an aggressive and complex cancer to treat. The family is raising funds in case Jake needs to access further treatment not available on the NHS to either keep the cancer from returning or clear the disease if his frontline treatment doesn't go to plan.

"In particular, we are interested in the Bivalent Vaccine clinical trial in New York. Our journey to date has had so many unexpected additional steps, we just want to ensure that we are ready for whatever the future may bring in terms of Jake's treatment," says Hannah.

Please help give Jake the best chance of beating this devastating disease.