Systemic inflammation, characterized by elevated levels of inflammatory markers in the body, is increasingly recognized as a significant contributor to the development and progression of Alzheimer's disease (AD). This inflammation can impact the brain, potentially accelerating the neurodegenerative processes associated with AD.

I research the connection between systemic and neuroinflammation and their effects on Alzheimer’s disease. We are researching the crosstalk between these 2 systems and its effect on the brain endothelial cellular molecular mechanisms controlling Blood Brain Barrier function, using both mouse (in-vivo) and cell culture (in-vitro) models.