Alex TLC is the only charity in the UK that provides invaluable support to anyone affected by a genetic leukodystrophy. Leukodystrophies are genetic disorders that mainly affect the white matter of the central nervous system (i.e. the brain or spinal cord). Most leukodystrophies are degenerative, causing symptoms such as impaired mobility, vision, speech and hearing, incontinence, inability to swallow and loss of cognitive skills. In some cases, they can sadly be terminal. By supporting my Give Up to Give Back challenge, you can help Alex TLC continue to make a real difference to those lives of those with leukodystrophies and their families.