Defending William Against DMD supports Duchenne UK a charity that has one clear aim to end Duchenne muscular dystrophy (DMD). DMD is a devastating muscle-wasting disease. It is the most common and severe form of muscular dystrophy. Diagnosed in childhood, it mainly affects boys. Started by families affected by the disease, Duchenne UK is the leading DMD charity in the UK: connecting the best researchers with industry, the NHS and families to advance and accelerate every stage of drug development. Together, we will end Duchenne.