Our Fierce Sisters journey started the day Elisabeth received a Stage IVb Ovarian Cancer diagnosis. From symptom to advanced high-grade serous carcinoma, it was a 22 terrifying days. Soon after, both Elisabeth and her sister Susan were identified as BRCA1 mutation carriers. Susan underwent preventive surgeries only to discover that she, too had the beginnings of this disease. It is hard to express the despair and powerlessness one feels to learn that there is no "cure" for ovarian cancer. Only 17% of advanced-stage patients are still alive by year five, and of those patients who do survive, there is a 90-95% recurrence rate. Also, BRCA1 carriers have a very high lifetime risk for breast and ovarian cancer, and there is no early detection test. Their despair turned to hope when they met Dr. Gottfried E. Konecny, an internationally recognized leader in ovarian cancer research, a physician-scientist, and a professor of medicine at the Geffen School of Medicine at UCLA. Given his