Clearing the Brain
Protein Clearance in Neurodegenerative Disease
Monday 30 October,
Venue: Woborn House Conference Centre, Tavistock Square
The symposium will be live streamed on 30 October and a live stream link will be posted on the day of the symposium.
The URL for the live stream is...
https://www.youtube.com/watch?v=2-8Q6klVMCk
Contributions are invited to support the symposium and student bursaries.
PROGRAMME
09:30 Registration, Tea / Coffee & Networking
10:15 Welcome: John Hardy
Session 1: Perivascular Clearance
Chairs: Cheryl Hawkes (Open University) & Tammaryn Lashley (UCL)
10:30 Roy Weller – University of Southampton
Pathology of cerebral amyloid angiopathy (CAA)
11:00 Roxana Carare – University of Southampton Testing the hypothesis that CAA results from a failure of
intramural periarterial drainage of fluid
11:40 Henrik Zetterberg – University College London Blood-based biomarkers for neuronal injury: an update on
promising and less promising candidates
12:00 Lunch Break
Session 2: Glymphatics
Chairs: Elizabeth Fisher (UCL) & Selina Wray (UCL)
13:00 Maiken Nedergaard – University of Copenhagen
The glymphatic system: Update and future perspectives
13:40 Jeffrey Iliff – Oregon Health and Science University
Evidence for the role of glymphatic dysfunction in human
Alzheimer’s disease
14:20 Mark Lythgoe – University College London
Untangling Alzheimer’s: Imaging brain clearance
14:40 Tea / Coffee Break & Poster Session
Session 3: Brain Lymphatics
Chairs: Helene Plun-Favreau (UCL) & Tom Hawkins (UCL)
15:10 David Attwell – University College London
Amyloid beta decreases brain energy supply by activating
pericytes to constrict capillaries
15:30 Jason Rihel – University College London
A novel lymphatic cell in the zebrafish meninges
15:50 Jonathan Kipnis – University of Virginia School of Medicine Meningeal lymphatic angle of neurological disorders
16:30 Short Comfort Break
16:35 Panel discussion with Roxana Carare, Roy Weller, Jeffrey Iliff,
Maiken Nedergaard & Jonathan Kipnis. Chaired by Mark Lythgoe.
17:20 Closing remarks
17:30 Drinks Reception & Networking
