My name is Joshua Monaghan and I’m 23 years old. When I was 16, I was diagnosed with Common Variable Immune Deficiency (CVID). That means my immune system doesn’t produce enough antibodies to protect me as it should, so I rely on weekly replacement therapy (immunoglobulin infusions) for the rest of my life.

Living with CVID isn’t easy. The treatment helps, but it comes with challenges. Some of the common side-effects of immunoglobulin therapy include:

1. Headache, fever, chills, fatigue, nausea.

2. Muscle or joint aches, and sometimes flu-like symptoms.

3. In more rare cases: issues like changes in blood pressure, kidney strain, or allergic reactions.

Even on days when I’m feeling the side-effects, I try not to let this define me. I believe that forcing myself to keep pushing physically, mentally, emotionally, helps me stay strong, both for myself and for others in the same situation.

That’s why I’m doing this marathon. I’m raising money for Immunodeficiency UK because:

1. Treatment access matters — It’s not just about my infusions; there are many people who don’t get enough support, who struggle with costs, or who don’t have the services they need.

2. Information & research help — Better understanding of immune deficiency helps improve treatments, reduce side effects, and improve quality of life.

3. Support & community — Chronic illness can be isolating. Organisations like Immunodeficiency UK provide vital support, awareness, and a voice to those whose immune systems can’t always protect them.

Fitness is one important way I’ve found to help fight infection: staying active, keeping strong, pushing through hard days. But fitness on its own isn’t enough. Treatment is a life-saver.

By supporting me in this marathon, you’re helping more than just me. You’re helping everyone who battles an immune deficiency, especially those whose access to treatment or support is tenuous.

Thank you for reading, thank you for caring. Every bit raised makes a real difference.