On the 28 June, I will be taking part in the Marmotte cycle challenge in the French Alps to raise money for the Marfan Trust in memory of my brother-in-law, Jonathan Grainger. Covering a distance of 177km (110 miles) with over 5,000m of climbing, this is likely to be my toughest ever day on a bike.

The Marmotte is one of the iconic cycling challenges in Europe. It includes long climbs, steep mountain roads and a real test of determination. Undertaking this challenge will allow me to fundraise in Jonathan's memory, and to support those living with Marfans.

Marfan syndrome is a genetic disorder of the body’s connective tissue that affects any gender, race or ethnic group. Connective tissue helps provide structure to the body, binding skin to muscle and muscle to bone. It provides the stretchy strength of tendons and ligaments around joints, and in blood vessel walls. In Marfans, a change in the fibrillin-producing gene, fibrillin-1, means that this protein is deficient in connective tissue throughout the body, creating an unusual stretchiness and weakness of tissues.

This has far-reaching implications and can affect the eyes, lungs, gut, nervous system, skeleton and, most dangerously, the cardiovascular system.

The Marfan Trust provides vital support for research, education and awareness. Its work helps improve understanding of Marfan syndrome and related conditions, and supports better outcomes for those living with them.

Every donation, whatever the amount, will help. Your support will not only help me get through the miles and mountain climbs ahead, but will also contribute to a cause that means a great deal to me and my family.