Thanks for taking the time to visit my JustGiving page. I'm taking part in a charity boxing match in Dundee and want to raise awareness for CADASIL and a charity (CADASIL Support UK ) that helps people with the condition, their families and carers.

https://cadasilsupportuk.co.uk/getsupport.html

What is CADASIL?

CADASIL is a rare inherited disorder that happens when the thickening of blood vessel walls blocks the flow of blood to the brain. CADASIL is short for “cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.”

Anyone can get CADASIL. The disorder is found worldwide, affects both men and women, and happens in people of all races and ethnicities.

CADASIL is caused by a mutation in the Notch3 gene. This mutation affects the small blood vessels in the white matter of the brain. Often there is a family history of the disorder, but it can also be caused by a spontaneous genetic mutation that happens for unknown reasons.

Symptoms and onset of the disorder can be different among people, but signs typically appear between the ages of 20 and 40 years. Some individuals may not show signs until later in life.

Donating through JustGiving is simple, fast and totally secure. Your details are safe with JustGiving - they'll never sell them on or send unwanted emails. Once you donate, they'll send your money directly to the charity. So it's the most efficient way to donate - saving time and cutting costs for the charity.