Invest in ME (IiME) is organising and funding a UK clinical treatment trial of rituximab by the best possible team for the job, led by Dr. Jo Cambridge at University College London (UCL), with world renowned expert Professor Jonathan Edwards in the role of Advisor to the charity. The initial £350k target was raised by IiME supporters from June 2013 to August 2014. THANK YOU! This included £50k to fund a preliminary study on B cells to identify likely responders to this treatment: prerequisite to the trial and a useful study in its own right. We now need to help IiME to raise a further £100k due to the promising early results from the B cell study, so the target on this page is now £450k. We can do it!

Rituximab is an immune modulating drug, which helped 67% of ME patients who took part in research in Norway to such a remarkable extent that the Norwegian Health Directorate apologised for the way ME patients have previously been treated. Even better results have now been found in a follow-up study, with higher doses giving a more prolonged effect. The Phase III multi-centre trial has begun in Norway in 2014, thanks to a successful fundraising campaign run by patients.  

This work needs to be validated in other countries and we thank you for your donations and sponsorship to help raise funds for the IiME/UCL UK trial. Donations go to a special IiME Rituximab Research Fund, separate from the general IIME Biomedical Research Fund, which is being used for other biomedical research projects. IiME is run by volunteers. There are no salaries and no funds will be used for charity admin.  All donations will be used in full to finance the Rituximab research. For text donations, text the code RTUX66 followed by the amount, to 70070.  We will keep you updated with progress and news about the fundraising and the trial. Find out more at:

Let's do it for ME is an awareness and fundraising campaign run by people with myalgic encephalomyelitis in support of the work of Invest in ME.  Find out more at: or email us at: 

Donating through JustGiving is simple, fast and totally secure. Your details are safe with JustGiving – they’ll never sell them on or send unwanted emails. Once you donate, they’ll send your money directly to the charity. So it’s the most efficient way to donate – saving time and cutting costs for the charity.

So please dig deep and donate now - thank you for your support. 

Updates 64

A fabulous further £50k pledge by the Hendrie Foundation. A new target of £520k to allow for the all-important prerequisite B-cell research. UCL team currently in Norway laising with researchers working on the Phase III multi-centre trials. UCL B-cell paper to be published soon.

27/09/15 02:54

May is ME Awareness Month. Thanks for all sponsorship & donations in response to supporters heroic awareness & fundraising efforts such as a great blog about research funding by John Mackay & Sophie Tennent's campaign (pictured in the gallery with the one and only Robbie Fowler).

15/05/15 04:43

£375k now raised, thanks to your sponsorship and including a generous anonymous donation of £1000 from Northern Ireland adding to the offline total raised on this page. Best wishes to everyone for the Easter Holiday Weekend and thanks so much for supporting this vital research.

04/04/15 01:21

At 82% of target. The total raised since patients launched the Let's Do It for ME campaign in support of IIME Charity Bomedical Research Funds has now topped £500k! Every penny goes on their research for diagnostic tests & treatments for this chronic disease. THANK YOU sponsors!

01/03/15 10:56

We see in the New Year with 81% of the target raised, courtesy of another generous (this time offline) donation of £1000 by FM-CFS Canada. HUGE THANKS & HAPPY NEW YEAR to all sponsors world-wide of this sorely-needed research for tests & treatments for myalgic encephalomyelitis.

01/01/15 06:14

Raising money for



Charity Registration No. 1114035

Invest in ME has as its objectives to change how myalgic encephalomyelitis (ME) is perceived and treated in the press, by health departments and by healthcare professionals. We aim to do this by raising funding for biomedical research and improving education about the disease.

Raising money for

Run by IiME

Charity Registration No. 1114035

Donations 509

Donation by Anonymous on 04/10/15

Donation by Anonymous on 27/09/15


Proceeds from 2 years (seasons) of selling plants from our front garden to passers by and from garden open days.

Donation by Alan and Pat Hutchinson on 23/09/15


+ £100.00 Gift Aid

Donation by Anonymous on 17/09/15


I can't afford much being a sufferer myself but I wanted to help. So grateful to people who are trying to help us get a successful treatment for this horrible illness. Thank you.

Donation by cheryl warrillow on 14/09/15


Donation by Anonymous on 13/09/15


Donation by Anonymous on 12/09/15


+ £7.50 Gift Aid

Hoping that Rituxamib works for ME

Donation by Sally on 10/09/15


+ £12.50 Gift Aid

Donation by Anonymous on 10/09/15


+ £125.00 Gift Aid

Donation by James Gargette on 10/09/15


+ £5.00 Gift Aid

Working towards the time when children lives are no longer devastated by M.E

Donation by Lynne Turner on 09/09/15

Donation by Anonymous on 05/09/15


+ £12.50 Gift Aid

Look forward to the results

Donation by Henry Anderson on 30/08/15


+ £2.50 Gift Aid

Thank you so much for doing this. I've waited a long time to see good biomedical research into ME in the UK.

Donation by Elizabeth Moon on 28/08/15


For Sue and Paul X

Donation by Laura Davison on 21/08/15


+ £6.25 Gift Aid

Donation by Anonymous on 18/08/15

Lets us hope this is the break through we've been waiting for (me -23 years)

Donation by Chris Dusgate on 17/08/15


+ £25.00 Gift Aid

For everyone with M.E.

Donation by Helen Brierley on 08/08/15


Donation by Anonymous on 07/08/15


Donation from a fundraising stall at our local village gala. Keep up the good work, and here's to hitting the next target. Xx

Donation by Sally Crowe and Caithness CFS/ME support on 03/08/15


+ £34.38 Gift Aid

Thank you, M. and I.

Donation by RRW + KJW on 03/08/15


For Elizabeth.

Donation by Margaret Tyson & Marian Wood on 02/08/15


+ £10.00 Gift Aid

Donation by Anonymous on 31/07/15


+ £2.50 Gift Aid

For Amy

Donation by Anonymous on 29/07/15


+ £75.00 Gift Aid

It's not alot but it's all I have. I hope you reach your target. X

Donation by amanda mango griffin on 28/07/15


Donation summary

  • * Online donations£20,577.65
  • Offline donations£437,584.35
  • Text donations£838.00
  • Total raised£459,000.00
  • Gift Aid£3,321.00

* Charities pay a small fee for our service. Find out how much it is and what we do for it.