Story

Invest in ME (IiME) is organising and funding a UK clinical treatment trial of rituximab in patients with ME (myalgic encephalomyelitis).  Rituximab acts by depleting B-cells and is used in therapy for blood cancer, rheumatoid arthritis and some other autoimmune diseases.  It helped 67% of ME patients who took part in trials in Norway to such a remarkable extent that the Norwegian Health Directorate apologised for the way ME patients have previously been treated. Even better results were found in follow-up studies, with higher doses giving a more prolonged effect.  A Phase III multi-centre trial is underway in Norway, thanks to a successful fundraising campaign run by patients. 

The first phase of the IiME UK rituximab research is a study of B-cells in ME patients compared with healthy volunteers,  recommended by Invest in ME Research Advisor, Professor Jonathan Edwards, as prerequisite to a UK clinical trial.  The study is led by Dr. Jo Cambridge at University College London (UCL) in collaboration with the rituximab researchers in Norway and other countries.  The first paper by the UCL team has now been published and the work continues, thanks to IiME and the charity's supporters fundraising, sponsoring & donating.  

Your donations to this page go to a special IiME Rituximab Research Fund, separate from the IiME Biomedical Research Fund, which is being used for other biomedical research projects. IiME is run by volunteers. There are no salaries and no funds will be used for charity admin.  All donations will be used in full to finance the rituximab research. For text donations, text the code RTUX66 followed by the amount (£1-£5 or £10) to 70070.   Find out more & keep up to date with news at: http://www.ukrituximabtrial.org/

Let's do it for ME is an awareness and fundraising campaign run by people with myalgic encephalomyelitis in support of the work of Invest in ME.  Find out more at: ldifme.org or email us at: fundraising4me@gmail.com 


Donating through JustGiving is simple, fast and totally secure. Your details are safe with JustGiving – they’ll never sell them on or send unwanted emails. Once you donate, they’ll send your money directly to the charity. So it’s the most efficient way to donate – saving time and cutting costs for the charity.

So please dig deep and donate now - thank you for your support! 

Updates 66

Invest in ME Rituximab Research Fund reaches £480k - http://ldifme.org/iime-rituximab-research-fund-reaches-480k/

06/04/16 12:31

£467,000 of £520,000 now raised. Thank you so much for your sponsorship of this ground-breaking research for tests & treatments for myalgic encephalomyelitis. Keep informed at www.ukrituximabtrial.org

06/12/15 01:26

A fabulous further £50k pledge by the Hendrie Foundation. A new target of £520k to allow for the all-important prerequisite B-cell research. UCL team currently in Norway laising with researchers working on the Phase III multi-centre trials. UCL B-cell paper to be published soon.

27/09/15 02:54

May is ME Awareness Month. Thanks for all sponsorship & donations in response to supporters heroic awareness & fundraising efforts such as a great blog about research funding by John Mackay & Sophie Tennent's campaign (pictured in the gallery with the one and only Robbie Fowler).

15/05/15 04:43

£375k now raised, thanks to your sponsorship and including a generous anonymous donation of £1000 from Northern Ireland adding to the offline total raised on this page. Best wishes to everyone for the Easter Holiday Weekend and thanks so much for supporting this vital research.

04/04/15 01:21

Raising money for

IiME

IiME

Charity Registration No. 1114035

Invest in ME has as its objectives to change how myalgic encephalomyelitis (ME) is perceived and treated in the press, by health departments and by healthcare professionals. We aim to do this by raising funding for biomedical research and improving education about the disease.

Raising money for

Run by IiME

Charity Registration No. 1114035

Donations 546

A tiny contribution but full of hope that my dear friend will soon have his wonderful life back.

Donation by Anonymous on 16/04/16

£20.00

+ £5.00 Gift Aid

After 25 years of severe ME,am hanging onto life by a thread My donation is for future generations so no one ever has to endure this living death.

Donation by Maureen on 15/04/16

£5.00

+ £1.25 Gift Aid

Had this for over 10 years now, it's completely ruined my life. This trial brings so much hope

Donation by Anonymous on 14/04/16

£20.00

+ £5.00 Gift Aid

text donation

Donation by Anonymous on 07/04/16

£3.00

via sms

Donation by Anonymous on 05/04/16

£50.00

+ £12.50 Gift Aid

Thank you Chris for all your help over the last few months. It has been so helpful to have someone professional to discuss problems with. Happy paragliding. Best wishes Jo

Donation by Jo P on 01/04/16

£150.00

+ £37.50 Gift Aid

This illness has ruined my life for 12 years but the Rituximab Trial gives me hope that, in my lifetime, there may be a cure or a treatment. Thank you for what you are doing for sufferers.

Donation by Vicki Cliffe on 30/03/16

£50.00

Donation by Anonymous on 22/03/16

$10.00

To Chris, In celebration of your birthday and in support of the trial. from Sandy, Leighton & Sarah

Donation by Karen on 21/03/16

£53.00

+ £13.25 Gift Aid

This research gives hope - let's make it happen

Donation by Andrew Biltcliffe on 19/03/16

£30.00

+ £7.50 Gift Aid

As an ME sufferer, this research is so important to me! Thank you

Donation by Sam on 16/03/16

£30.00

Thank you!

Donation by Lidia Thompson on 16/03/16

£50.00

+ £12.50 Gift Aid

Donation by Jean & Dave Dusgate on 15/03/16

£100.00

+ £25.00 Gift Aid

Happy Birthday Chris! with lots and lots of love

Donation by Karen on 15/03/16

£1,200.00

+ £300.00 Gift Aid

More to come, keep up the good work! x

Donation by Ainsley on 12/03/16

£5.00

+ £1.25 Gift Aid

More to follow, keep up the good work!

Donation by Anonymous on 10/03/16

£10.00

+ £2.50 Gift Aid

Donation by Anonymous on 10/03/16

£100.00

A bit of hope for my daughter who has been ill for 28 years. Good luck with the fundraising x

Donation by Estelle Mitchell on 09/03/16

£20.00

Donation by Rainbow Finch on 07/03/16

£10.00

Donation by Anonymous on 06/03/16

£50.00

+ £12.50 Gift Aid

text donation

Donation by Anonymous on 26/02/16

£3.00

via sms

text donation

Donation by Anonymous on 10/02/16

£10.00

+ £2.50 Gift Aid

via sms

Donation by Anonymous on 10/02/16

£20.00

+ £5.00 Gift Aid

text donation

Donation by Anonymous on 05/02/16

£3.00

via sms

text donation

Donation by Anonymous on 03/02/16

£4.00

via sms

Donation summary

  • * Online donations£22,805.90
  • Offline donations£459,305.10
  • Text donations£889.00
  • Total raised£483,000.00
  • Gift Aid£3,809.75

* Charities pay a small fee for our service. Find out how much it is and what we do for it.