Myalgic encephalomyelitis (ME), also called chronic fatigue syndrome (ME/CFS), is estimated to affect about 400,000 people in the UK and 67 million people worldwide.

Its key feature, called post-exertional malaise, is a delayed dramatic worsening of symptoms following minor physical or mental effort. Other symptoms include pain, brain fog and extreme energy limitation that does not improve with rest. It is a female-dominant disease, often triggered by infection. Its causes are unknown and there is currently no diagnostic test or cure.

The ME/CFS research team at the University of Edinburgh is investigating the genetic causes and possible biomarkers of ME/CFS. Their work includes DecodeME - the largest study of ME/CFS in the world – and is improved by Patient and Public Involvement.

By donating to ME/CFS research, you will help us find the genetic causes of why people become ill, better understand the disease and ultimately find treatments.

Thank you for your support.